Medical Laboratory Scientist ASCP Practice Exam 2026 – Complete Study Guide

The estimate of the percentage of individuals in the overall population who are Rh negative is approximately 15%. This figure is based on data that indicates the distribution of the Rh factor varies among different ethnic and racial groups. For instance, about 15% of Caucasians are Rh negative, while this percentage can be lower in other populations, such as African or Asian descent, where the prevalence of Rh negativity is typically lower.

It's important to recognize that while the Rh negative blood type is less common than Rh positive, its prevalence is significant within certain populations, which is why understanding the demographics of your patient population in a clinical setting is crucial for blood transfusions and organ donations. Understanding Rh factor distribution also aids in prenatal care and prevents hemolytic disease of the newborn, where maternal antibodies may attack fetal red blood cells if there is an Rh incompatibility.