Medical Laboratory Scientist ASCP Practice Exam 2025 – Complete Study Guide

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Question: 1 / 400

In an immunoassay with high specificity but low sensitivity, what is a true statement?

Identifies all cases of the disease

Accurately identifies the absence of disease

In an immunoassay characterized by high specificity but low sensitivity, the statement that accurately reflects this situation is that it can accurately identify the absence of disease. High specificity indicates that the test is very good at correctly identifying true negative cases, meaning that if the test result is negative, there is a high likelihood that the individual does not have the disease.

Sensitivity, on the other hand, relates to the test's ability to detect true positive cases; therefore, low sensitivity means that some individuals who actually have the disease may not be identified as positive by the test. This can lead to missed diagnoses. However, since the test is specific, if it says a patient does not have the disease, it is reliable in that assertion, minimizing the chances of false positives.

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Produces many false-positive results

Identifies some cases of the disease

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