Medical Laboratory Scientist ASCP Practice Exam 2026 – Complete Study Guide

Question: 1 / 400

What condition is indicated by low HCO3 levels?

Alkalosis

Acidosis

Low HCO3 levels indicate an accumulation of acidity in the blood, typically seen in metabolic acidosis. HCO3 (bicarbonate) acts as a buffer in the blood; when its levels are low, it signifies that the body is either producing excess acid or not adequately eliminating acid. Conditions causing metabolic acidosis may include diabetic ketoacidosis, renal failure, or lactic acidosis, among others. This is in contrast to alkalosis states, where bicarbonate levels would be high, reflecting an excess of bicarbonate or a loss of hydrogen ions. Thus, low HCO3 is a key marker for identifying acidosis, supporting the notion that the correct answer pertains to this state of acidemia.

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Compensated respiratory acidosis

Metabolic alkalosis

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