Medical Laboratory Scientist ASCP Practice Exam 2025 – Complete Study Guide

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How long after collection must granulocyte concentrates be administered?

12 hours

24 hours

Granulocyte concentrates are a type of blood product derived from the leukapheresis process, where white blood cells, particularly granulocytes, are collected and used for transfusions, often in patients who have low white blood cell counts due to conditions such as leukemia or after chemotherapy. The administration of these concentrates is critical for their effectiveness in treating infections or other complications related to neutropenia.

The correct option indicates that granulocyte concentrates should be administered within 24 hours of collection. This time frame is necessary because granulocytes are especially sensitive to storage conditions and can quickly lose their viability and functional capacity if not used promptly. After about 24 hours, the granulocytes may undergo changes that significantly reduce their effectiveness, leading to diminished outcomes for patients who rely on these transfusions to strengthen their immune response.

The other options (12, 36, and 48 hours) do not align with established guidelines for the practical use of granulocyte concentrates, which emphasize the importance of timely administration to maintain the integrity and efficacy of the cells for the patients receiving them.

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36 hours

48 hours

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